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translocations or amplifications along with the genomic alterations by now existing in the initial CLL, but lack the widespread mutations noticed in Most important DLBCL indicating they may perhaps correspond to a special biological category.

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Are BTK and PLCG2 mutations important and enough for ibrutinib resistance in Continual lymphocytic leukemia?

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mutations specified The truth that, as defined under, CLL therapy relies around the presence or absence of those mutations. The existing consensus is usually that, in addition to clonal mutations, subclonal mutations that has a variant allelic frequency starting from five to 10% (and for that reason down below the brink of detection by standard molecular approaches) is also claimed, Whilst These that has a variant allelic frequency lessen than 5% must not, but there's Considerably controversy all over these difficulties which suggestion may well adjust Down the road.

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で近接ビーコンを判別する方法を提案し, 屋内位置測位システムに組み込み評価した結果について報告をする．

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